Jeuveau

What is Jeuveau?

Jeuveau, aka “Newtox,” is an FDA-approved neurotoxin for use in aesthetic medicine. It’s a botulinum toxin type, similar to Botox, made in a lab to mimic the same effects as a natural neurotoxin.

Jeuveau is one of the cosmetic injections commonly used to treat frown lines, glabellar lines, expression lines, and other facial wrinkles.

How does Jeuveau Work?

Jeuveau injections contain FDA-approved neuromodulators that relax the small muscle groups responsible for causing wrinkles. Once injected into the treatment site, the botulinum toxin type contained in Jeuveau temporarily blocks chemical signals to the nerve cells. Without these signals, the nerve cells don’t contract. This is how Jeuveau injections effectively smooth and relax facial lines.

How do Jeuveau and Botox compare?

Cosmetic use of Juveau and Botox are largely targeted at the same issues: glabellar lines, frown lines, and other facial wrinkles. Botulinum toxin in both medicines is an active, FDA-approved ingredient that makes each shot effective.

The main difference between Jeuveau and Botox is that Jeuveau targets a different chemical compound in the neuromodulator family.

Botox injections contain a botulinum toxin type called onabotulinumtoxinA. This toxin binds to a protein produced by nerve cells and is responsible for triggering muscle contractions.

Jeuveau injections use a botulinum toxin called PrabotulinumtoxinA. Its mode of action doesn’t directly affect muscle contractions; instead, Jeuveau works by preventing the neurotransmitter acetylcholine from binding with its receptor on cell surfaces, called the cholinergic receptor. This prevents chemical signals from being sent to the brain and muscles, thus relaxing the facial lines caused by those signals.

How long does Jeuveau last?

Results from Jeuveau injections can last 3 to 6 months depending on the patient.

For maintenance, many doctors recommend returning for a second round of Jeuveau treatment the first 3-4 months after your initial session. After a couple of additional injections, patients can return for boosters every 3-6 months.

How can I extend my Jeuveau results?

With each consecutive bout of injections, the muscle fibers contract and relax less. The more you train your muscles with Jeuveau, the lower their tension will be over time which may make for a longer-lasting effect!

Even though FDA-approved neuromodulators wear off, you can optimize and extend results by doing the following:

• Consult with your doctor to create a long-term treatment plan to enjoy more cumulative results and keep your face looking relaxed and smooth.
• Make sure to prepare for your Jeuveau treatment. Avoid blood thinners and alcohol to reduce the chances of bruising.
• Stick to the post-treatment guidelines and avoid scrubbing/massaging/exfoliating the area(s) where you were injected for the first 24 hours.
• Do your best to stay away from heat, as it can diminish the effects of botulinum toxins. Refrain from heated skin treatments for a minimum of 3 days after your Jeuveau session.
• Stay in the shade. While sunshine doesn’t directly affect Jeuveau, it weakens and thins the skin, making it more susceptible to wrinkling

What can I expect from a Jeuveau treatment?

Prior to your first injection, your medical provider will consult with you to determine which areas need treatment and how many units of medicine you’ll need.

After receiving the injections, you’ll most likely be able to resume your day immediately.

For most patients Jeuveau takes effect within 2-3 days post-treatment, otherwise, results are usually visible in about a week. Initially, you may experience minor bruising at the injection site that will dissipate over time.

After the Jeuveau treatment, most doctors recommend patients avoid strenuous exercise or heavy lifting for 24 hours following treatment. You should also keep from touching your face for the first 4 hours; no massages, facials, or makeup application for a full day after your injection.

What are the risks and side effects of Jeuveau?

In Jeuveau clinical trials no serious risks or side effects were observed, however, common side effects found in a small percentage of study participants, include:

• Bruising
• Headaches

What else does Jeuveau treat?

Jeuveau is most commonly used to treat frown lines, however, it is also being sought for use in the treatment of several additional aesthetic indications including migraine headaches, overactive bladder, excessive sweating, and urinary incontinence. As it has not received FDA approval for these areas, however, applying Jeuveau to them would be considered off-label use.

Who should not get Jeuveau?

The FDA-approved safety and effectiveness of Jeuveau have not been established for use in pediatric patients, patients with certain infectious diseases, pregnant women, and breastfeeding mothers.

If you’ve ever had an allergic reaction to a botulinum toxin while treating expression lines (or in general) Jeuveau is likely not for you.

Consult with your doctor before pursuing treatment with Jeuveau.